An injection prp procedure (abbreviated from Plateletrichplasma, that is, blood plasma enriched with platelets.), Involving the introduction of autogenous plasma locally, aimed at accelerating the regeneration and stimulating the growth of the body's own cells.
The method is quite innovative, but already at this stage it has demonstrated tremendous results. Also prp-therapy is referred to as non-surgical methods of treatment. Platelets contain a number of bioactive molecules, such as platelet growth factor (PDGF, isoforms AA, AB, BB), transforming factor β (TGF β), vascular endothelial factor (VEGF), insulin-like growth factor (IGF), etc.
The active development of the technique began in 1997-1998, when articles by American scientists Whitman and Marx appeared independently of each other, devoted to the use of platelet-rich plasma in maxillofacial surgery (although, if you trace back to the origins, the first work in this direction fell on another 70 years of the last century).
The technique has found its application in many branches of medicine, from cosmetology to neurosurgery, but it has become especially relevant in sports medicine, traumatology and orthopedics. Platelet-rich plasma is obtained from the patient's own blood, subjected to centrifugation.
Advantages of the method: no allergies, as the patient's own tissues are used; there is no possibility for transmission of infection with blood, since, again, own (homologous) blood is used; there are no side effects and systemic effects - effects on the liver, kidneys and other organs, as is the case with drugs; the minimum number of possible complications.
Preparation for the PRP procedure The effectiveness of the procedure directly depends on the quality of the plasma obtained. At least 2 weeks before the PRP of the joints, you must: stop taking medications that change blood clotting (including acetylsalicylic acid); stop taking other non-steroidal anti-inflammatory drugs (which are almost always prescribed for joint pathology to relieve pain); exclude alcohol and smoking (if it does not work for 2 weeks, then at least a day before the procedure); diversify the diet, including sources of vitamins B (whole grains, black bread) and C (sauerkraut, black currant), or take a multivitamin.
Stages of the procedure:
- Venous blood collection from 20 to 50 ml.
- The blood is placed in a special tube for easy separation of fractions;
- The blood is placed in a centrifuge;
- A collection of 3-5 ml of platelet-rich plasma is carried out;
- The drug is administered locally as prescribed by a doctor.
PRP therapy involves from 3 to 7 procedures with an interval of 7 days.
We do not recommend visiting saunas, baths or solarium within 72 hours after the procedure.
Indications for PRP-therapy: Sports injuries of ligaments, tendons and muscles (sprains, tears); sports injuries (chronic); arthritis; arthrosis; tendovaginitis; plantar fasciitis (heel spur); other chronic pathologies of tendons and ligaments, With difficult healing ulcers, weeping eczema. Recently, PRP therapy has become widespread in neurosurgery, and in particular in a conservative approach in the treatment of hernias and protrusions of the intervertebral discs of the vertebral column.
Current application in orthopedics - speaking of cartilaginous tissue, it itself has a rather limited ability to restore, because there are no vessels directly feeding it, nutrition is due to the synovial fluid located in the joint cavity. That is why, for effective therapy of joints, medicinal substances are injected directly into their joint cavity. And therefore, the ability to deliver substances that activate regeneration directly to the cartilage could not fail to attract the attention of specialists. In addition, activated plasma reduces inflammation and rapidly reduces pain, one of the main problems in chronic joint pathologies.
Contraindications to PRP therapy can be temporary (relative) and absolute. Relative contraindications: acute infection, including ARVI, herpesvirus infection; body temperature above 38 ° C; the use of drugs that affect the blood coagulation system. Absolute contraindications: oncological pathology; autoimmune diseases; blood clotting disorders; thrombocytopenia (low platelet count) and thrombocytopathy (abnormal platelet function); blood hemoglobin below 90 g / l; individual intolerance to sodium citrate (a substance that prevents blood clotting in a prp tube); immunodeficiency; sepsis.
After PRP-therapy is expected: improvement of blood circulation in the area of the affected joint; elimination of spasm of the muscles surrounding the joint; acceleration of cartilage recovery both due to biologically active substances that regulate this process, and by supplying it with the necessary components; normalization of the composition of the joint fluid; acceleration of rehabilitation after injury, surgery.