Many other drugs can cause dangerous side effects or death when taken with narcotic (opioid) medications. If you use any other medications, make sure your doctor is aware of this. Drugs that can interact with Lortab include:

  • other narcotic medications prescribed by a doctor, such as opioid pain relievers or cough medicines
  • medicines that make you sleepy or slow your breathing, such as a sleeping pill, muscle relaxer, sedative, tranquilizer, or antipsychotic medicine
  • drugs that affect the serotonin levels in your body, such as medicine for depression, migraine headaches, Parkinson’s disease, serious infections, or prevention of nausea and vomiting