Symptoms of TB Disease https://www.nivabupa.com/disease-articles/tuberculosis-and-its-symptoms.html Symptoms of TB Disease include persistent cough lasting more than three weeks, chest pain, and coughing up blood or sputum. Other signs may include fever, night sweats, fatigue, weight loss, and loss of appetite. If left untreated, tuberculosis can spread to other organs, making early detection and treatment essential for preventing complications.